Pharmacology and Nursing Process Practice Exam 2025 – Complete Prep Guide

Eplerenone is a medication used to treat high blood pressure and heart failure. The reason why this medication is contraindicated in patients with severe renal impairment is because it is primarily eliminated through the kidneys. In patients with severe renal impairment, the medication may not be effectively cleared from the body, leading to a build-up of the drug and potential adverse effects.

Option B, Bosentan, is a medication used to treat pulmonary arterial hypertension. While it is not identified as being contraindicated in patients with severe renal impairment, caution should be taken when prescribing this medication to these patients.

Option C, Treprostinil, is also a medication used to treat pulmonary arterial hypertension and does not have a specific contraindication for patients with severe renal impairment. However, patients with impaired renal function may experience increased side effects such as headache and hypotension.

Option D,